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Year : 2015  |  Volume : 1  |  Issue : 2  |  Page : 31-34

A Study on Pathophysiology, Diagnostic and Treatment Procedures for Preeclampsia Syndrome

1 Department of Medical Sciences, Young Researchers and Elites Club, Qom Branch, Islamic Azad University, Qom, Iran
2 Chronic Diseases Care Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Golestan BLv Ahvaz, Iran
3 Health Policy and Promotion Research Center, Qom University of Medical Sciences, Qom, Iran

Correspondence Address:
Dr. Siamak Mohebi
Health Policy and Promotion Research Center, Qom University of Medical Sciences, Qom
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Source of Support: None, Conflict of Interest: None

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Preeclampsia falls under a top priority pursued by the World Health Organisation. Despite several decades of extensive research into its aetiology, this disease has remained unknown. It seems that more than one pathophysiological factor contributes to increased blood pressure. With regard to the importance of preeclampsia, researchers have attempted to examine the hypotheses concerning the pathophysiology of the disease so as to obtain a broad approach to causes, possible treatments and early diagnosis. This study is based on the literature review relying on a total of 61 papers retrieved from several information banks and academic search engines, including, PubMed, Proquest, Elsevier and Scopus. These papers were selected through a number of designs such as cross-sectional, cohort, clinical trial and systematic review. Furthermore, the Persian papers were selected from databases such as Iranmedex and Medlib, as well as article search, on local web-based scientific journals. The investigation revealed that zinc plays a key role in prevention from preeclampsia. On the other hand, preeclampsia can be diagnosed, and potential risks can be evaluated based on measurements made during periods sooner than the third trimester. Moreover, preeclampsia can be treated by prescribing vitamin supplements and modification of diet. Furthermore, the additional supply of calcium has been useful in the treatment of preeclampsia in some areas, while it might be ineffective in some others. Finally, it can be argued that higher beta-human chorionic gonadotropin can indicate the severity of the disease, but it is of little value in early diagnosis of the medical condition. Having examined the studies done so far, it was found out that there are numerous parameters for early diagnosis and treatment of preeclampsia, even though they are far from comprehensive. These methods seem to be responding differently in every region. Therefore, it is recommended that such parameters be evaluated in various regions so as to pinpoint their effects.

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